0:36 Obesity drugs and contraindications
1:36 Who would be excluded in trials to evaluate?
2:36 Hard to keep all in mind when prescribing
3:20 Cervical cancer mortality in those 25 or younger
4:20 Reduction in death after HPV vaccination
5:27 Pneumococcal vaccination
6:27 Can we fractionate the dose and remain effective
7:27 Don't know if lower dose is durable
8:28 Done in healthy infants
8:48 Combination therapy for one form of colorectal cancer
9:48 Nivolumab plus ipilumimab
10:50 Outcome bad with chemotherapy
11:30 There are side effects
12:23 End
0:40 Reducing lipoprotein(a)
1:40 Oral medicine prevents two components from binding
2:40 What proportion have this issue?
2:54 Polygenic risk scores and heart disease risk
3:54 Ended up with 46 scores
4:54 40-50% of risks involved with genes
5:56 Two medicines after heart attack
6:56 No benefit in all comers with heart attack
7:50 Nationwide genetic carrier screening
8:50 9107 couples completed
9:50 Wide number of diseases screened
10:50 Genetic counselor for those with increased risk
12:18 End
0:40 Diabetes treatment, kidney stones, gout
1:40 To prevent kidney stones, need to treat 20
2:40 How do other diabetes meds compare?
3:42 Multi morbidity, hospital admission and death
4:42 Sort combinations to calculate risk
5:42 Inadequate resources in the winter
6:44 Person-centered approach needed
7:10 LDL not the whole story
8:10 Risk related to both LDL and Lp(a)
9:10 Recommend Lp(a) measurement
9:36 Frailty as a predictor of dementia
10:39 Risk varied from 20-75% increased risk
11:42 Number of factors to assess frailty
13:09 End
0:40 Sugar rationing in first 1,000 days of life
1:41 Infant formula and solids
2:40 Divide in utero and post exposure
3:22 Sudden cardiac death after heart attack prediction
4:22 Something besides decreased heart function
5:15 Very early medication abortion
6:15 Rule out ectopic pregnancy
7:15 42-day period
8:16 Okay if probably in the uterus
9:00 FDA recommendations on inferior vena cava filters
10:00 Removal is needed
11:00 Less likely to be removed in older people
12:18 End
0:45 Oral health and other health outcomes
1:45 22,000 participants
2:45 Cancer, cognitive dysfunction related
3:20 Electric fans and core temperature in older adults
4:20 Aging population and climate change
5:18 Hearing loss and Parkinson's disease
6:18 Categorize severity of hearing loss
7:20 Mechanism for hearing and PD?
8:21 Current strategies to help with high prescription drug costs
9:25 Major barrier to optimal medical management
10:21 Artificially high prices for generics
11:25 Many patients don't know about
12:32 End
0:37 Tobacco use among U.S. youth
1:34 One in 10 high school students
2:34 How much it costs to use tobacco
3:06 Paternal metformin use in men and offspring malformations
4:08 Corrected data showed no risk
5:08 Those who used metformin older
6:10 Treatment of opioid use disorder
7:10 Which less likely to result in discontinuation
8:10 Mortality very low
9:03 Can we deprescribe in persons with dementia
10:03 Mailer to patient, physician or usual care
0:49 Rainfall events and daily mortality analysis
1:49 How quickly might such an event recur?
2:50 Some of the mechanisms
3:44 HIV+ kidney donors
4:49 Been doing in South Africa since 2008
5:10 Identifying risk for preeclampsia
6:12 High systemic vascular resistance
7:14 Did not predict late term
8:10 Noninvasive test
8:21 Treatment of MASH
9:20 Death of liver cells and inflammation
10:30 Increased rate of COVID-19 infection
11:37 End
0:42 U.K. Biobank study on happiness and heart disease risk
1:42 Indirect and direct effects
2:42 Enhance well-being
3:00 Ultraprocessed foods and diabetes risk
4:00 NOVA classification for foods
5:00 10% decrease if you replace
6:00 Do men with elevated PSA need prostate biopsy?
7:00 Followed over four years
8:00 Cost effective compared with biopsy
8:25 AACR report on cancer
9:25 More than 2 million new cases of cancer in 2024
10:25 40% attributable to preventable risk factors
11:25 Understand pathways by which cancer develops
12:42 End
0:40 High-dose prescription amphetamines and psychosis
1:40 Compared to hospitalizations for other conditions
2:40 Stay under dose of 40mg
3:30 Characteristics of opioid overdose, EMS encounters and U.S. youth
4:30 Almost all in 18-24 years of age group
5:31 60% occurred at home
6:32 Rapid malaria test and child mortality
7:35 Each associated with increased antimalarial drugs
8:35 Issue with the study
9:15 Triple-negative breast cancer treatment
10:15 Pembrolizumab or not
11:18 Adverse events related to treatment
12:36 End
0:44 Time from approval to reimbursement for drugs
1:43 Over 290 new drugs and all regulatory bodies
2:48 Quixotic in U.S.
3:10 False-positive results on mammogram and return
4:10 Varied based on ethnicity
5:10 Not coming back after false positive
6:10 Higher out-of-pocket costs
6:44 RSV vaccination and hospitalizations
7:44 Individuals hospitalized with acute respiratory illness
8:44 Receive a single dose
9:22 Inhaler impact on environment
10:22 U.K. pales in comparison to U.S.
11:22 Dry powder and soft mist inhaler alternative
12:16 End
0:41 A single blood test for CVD in women over 30 years
1:40 Each biomarker provided additive information
2:41 Every quintile increase
3:31 Semaglutide and ID risk
4:31 COVID-19 emerged during study
5:32 Reduced all-cause mortality 19%
6:34 Stopping beta blockers after heart attack
7:35 Increased risk of chest pain
8:35 Should be looked at earlier?
8:57 Comparing FIT tests
9:57 Huge variation in the tests
10:57 Will require more colonoscopies
11:52 Repeated testing improves sensitivity
12:48 End
0:47 COVID vaccination and myocarditis
1:49 25 to 31 years of age, most of them male
2:49 Don't be dissuaded from vaccination
3:01 Long-term care facilities and wastewater surveillance
4:01 Compared with clinical picture
5:03 Negative predictive value really good
6:06 Heat-related deaths in the U.S.
7:06 People who are employed where heat is an issue
8:07 Shifting the workday
8:26 Treating vasomotor symptoms in menopause
9:26 Took a long time to accrue
10:32 Fifty percent reduction
11:32 Benefits to hormone therapy
12:40 End
0:41 Amino acids for kidney protection during heart surgery
1:40 Intravenous infusion begun at time of surgery
2:40 May increase blood flow
3:20 Use of tranexemic acid during liver resection
4:20 Blood loss similar
5:20 Can reduce blood loss in seepage
6:00 EDTA chelation therapy in people with diabetes and heart attack
7:00 Either placebo or EDTA over 40 weeks
7:46 Suicidality in spouses of patients with cancer
8:45 Suicide attempt higher
9:45 Within a year after diagnosis
10:45 How to improve screening
11:54 End
0:41 Two reports on brain-computer interface
1:41 Implant just below the skull
2:32 Mortality in the U.S. in comparison with other Anglophone countries
3:31 Between ages of 45 and 84
4:31 Lower deaths prior to 45
5:31 Females don't fare as well regardless
5:45 Oral antibiotics and skin reactions
6:45 Three times higher for sulfonamides
7:45 Older age associated with polypharmacy
8:15 Plant and animal fat intake and mortality
9:15 Animal fat conferred increased risk
10:15 Biological plausibility
11:15 Beans and legumes
12:37 End
0:36 Blood tests for Alzheimer's
1:35 Predicting with a blood test accurate 91%
2:35 Less likely than just demographic data
3:30 Squamous cell carcinoma
4:30 Standardize guidelines
5:34 Common cancer excluded from tumor registries
6:15 CVD risk assessment
7:15 Less diabetes secondary to statins
8:15 7.5% risk should be modified?
9:20 Methotrexate for knee osteoarthritis
10:21 Addition did decrease knee pain
11:25 With elevated C-reactive protein
12:28 End
0:41 Firearm injuries
1:41 252,000 injuries
2:40 Suffered 61.5% of firearm assaults
3:15 Another indication for semaglutide?
4:15 Tobacco use disorder
5:15 Both with and without obesity
6:10 HIV prevention in women
7:10 Adolescent and young women in Africa
8:10 Coincidence of other STIs
8:44 Benefits of bilateral mastectomy
9:45 According to surgical approach
10:50 About 7% recurrence regardless
11:55 Table this strategy
12:55 End
0:38 Cash payments and health care utilization
1:38 Biomarker measurement
2:38 No effect on COVID-19 vaccination
3:38 Enable healthier choices
4:38 Didn't offset costs of program
5:03 AI and primary diabetes care
6:04 Compared with PCPs and endocrinology residents
7:04 Only four weeks of follow-up
7:25 Sleep patterns and risk of chronic disease
8:25 Fractured sleep positively associated
9:25 Longer follow-up needed
10:25 Irregularity and duration
11:01 Antibodies to treat ulcerative colitis
12:05 IV use of antibody
13:28 End
0:53 COVID-19 infection and Paxlovid
1:49 Did not reduce infection risk
2:51 Not noticed a difference with variants
3:14 Nasal sprays, behavioral interventions for URI
4:14 Stress management might help
5:14 Reduced antibiotic use
6:14 Stress reduction makes us less susceptible
6:35 Type 1 diabetes and COVID-19 infection
7:32 Attacks pancreas and accelerates progression
8:32 Same thing in adults?
8:42 Endometriosis and ovarian cancer risk
9:44 597 women with ovarian cancer
10:45 If they have same origin, it might provide insight
11:45 Arises in the fallopian tubes
12:35 End
0:40 Hospital-at-home care
1:40 Recover faster at home
2:41 Nicotine pouch use nationally
3:41 Assessed smoking status
4:41 Mouth lesions possible
5:32 Medication to mitigate multiple diseases in people with diabetes
6:33 Reduced death by cardiac causes by 30%
7:33 Few patients received both medications
8:08 A monoclonal antibody to help kidney transplant rejection
9:08 Nine infusions of the antibody
10:08 Might have to take over the long haul
11:08 More precise antibody possible
12:24 End
0:40 Trends in CVD in 22 million people in the U.K.
1:40 Overall decrease in some by 30%
2:40 Atrial fibrillation most common now
3:40 Some associated with aging
4:22 Routine screening EKGs
5:22 Is an association with subsequent CVD
6:20 Does not imply routine screening EKG
6:40 Preventing chemotherapy-induced neuropathy
7:40 Two types of exercise and treatment as usual
8:41 Something that can be routinely done
9:40 Continuing exercise may help
10:14 Treatment for opioid use disorder
11:15 55% receive any treatment at all
12:15 Barriers as part of health care system
13:16 End
0:33 Overuse of aspirin for primary prevention
1:32 Discouraged use in those over 75
2:32 Our listeners need to talk with their doctor
2:52 Gestational diabetes management
3:52 Increased C-sections, macrosomia
4:52 Start in pre-pregnancy period
5:52 Eight- to 10-fold risk
6:54 Acute liver injury and medications
7:54 Seventeen medications associated
8:54 Six biotypes in depression and anxiety
9:54 Task and no-task brain scans
10:52 Large number of things contribute
11:52 MRI before and after treatment
12:41 End
0:36 Expanding the window for treating ischemic stroke
1:33 Complete recovery 10% more
2:33 Routine CT scanning
2:44 Comparing two agents to treat ischemic stroke
3:44 More in the reteplase group had hemorrhage
4:45 Dosing based on heart attack experience
5:24 Preventing surgical site infections
6:24 Up to a year after cardiac surgery
7:24 May look for staph
7:44 Interventions for high BMI in children and adolescents
8:46 Give a B recommendation to behavioral interventions
9:45 Don't address bariatric surgery
10:45 Policy changes needed
11:45 Increased risk of early death
12:12 End
0:40 Cancers subsequent to CAR-T therapy
1:40 Only one person with a T cell cancer
2:40 Must do large populations to identify risk
3:15 Preoxygenation before intubation
4:15 More hypoxemia in oxygen mask group
5:15 Takes a little more time
6:09 Can nurses control blood pressure post stroke in Black and Hispanic patients
7:10 450 participants who'd had a stroke
8:10 Nurses talked about lifestyle in addition to blood pressure
8:50 Training eyes to slow down myopia in kids
9:50 Occurring globally
10:50 Myopia is nearsightedness
11:50 Employ computers to treat
12:31 End
0:44 Inflammation in arteries and cardiovascular events
1:41 Over 40,000 patients
2:45 More inflamed arteries, the more the risk
3:00 IBS, diet and medication
4:00 Three arms: two diets and optimized medication
5:03 Diets both better than medication
6:04 Wheat-free and gluten-free
7:00 Long-term outcomes in prostate cancer with active surveillance
8:04 Ten-year incidence of metastasis
9:11 Stepped palliative care for patients with lung cancer
10:12 Those with a ten point or greater decline
11:12 Over 24 weeks
12:18 End
0:48 Statins in old and very old
1:48 Increased risk for muscle pain or liver disease
2:48 Started on a statin
3:20 Maternal fluoride levels and neurobehavior in children
4:22 Increase in biomarker results in increased issues in kids
5:20 Parents score behavioral issues
6:16 Hypertension after kidney donation
7:18 Does hyperfiltration compromise?
8:19 Liver attempts to regenerate
9:10 Are mental health issues transmissible?
10:10 713,000+ in cohort
11:10 These issues cluster
12:10 Normalization of mental disorders
13:17 End
0:40 Implications of race adjustment in lung function equations
1:40 Over 12 million reclassified for lung function
2:40 Can be other confounders
3:40 Would differentiate race
4:40 There are race-based conditions
5:00 Survival benefit with cancer clinical trials
6:00 Quality of the trials
7:00 Routinely apply guidelines
7:30 Dispensing GLP-1 agonists to young
8:30 Three approved for Type 2 diabetes in adolescents
9:30 600% increase in use
10:05 Early diagnosis of COPD and asthma
11:05 Refer to pulmonologist
12:33 End
0:40 Improving assessment of cardiovascular risk
1:40 Trip through electronic medical record
2:40 Some cost and side effects
3:00 Association of ultra-processed foods with mortality
4:00 4% higher all-cause mortality
5:00 Surprised that cancer and CVD mortality not increased
6:00 Evidence in other studies for demyelination
6:36 New treatment for high triglycerides
7:40 Injected medication
8:40 Doesn't lower cholesterol
9:00 Low testosterone in men and mortality
10:00 Low testosterone increased mortality
11:04 Less binding globulin?
12:55 End
0:34 Sickle cell treatment
1:34 Take out progenitor cells
2:34 Side effects of treatment and cost
3:32 Significantly decreases survival
3:43 Racial and ethnic differences in mortality in U.S. youth
4:45 About twice as high among other ethnicities
5:48 Black youth eight times more likely to die of asthma
6:40 Treatment of very large strokes
7:40 333 patients within six hours
8:45 Practice changing
9:00 Breast cancer screening guidelines update
10:00 Older women and additional screening not known
11:00 Don't apply to some women
12:05 End
0:45 Two of the newer medicines for diabetes taken together
1:40 Over 15,000 people
2:40 Seem to have so many global impacts
3:05 Medicare drug price negotiation loophole
4:05 Very impressive results
5:05 Federal appeals court ruling
6:05 Exempts from negotiations
6:23 Diagnostic error in mental health
7:23 Mistake a physical illness
8:25 Neomycin intranasally
9:25 Sars-CoV2 and influenza A
10:25 Reduced infection and transmission
11:20 Widely available and generic
12:24 End
0:41 Atrial fibrillation and its complications
1:41 Increased risk factors
2:41 Treat with medication or ablation
3:30 Autism heritability in males and females
4:30 No support for environmental shared factors
5:33 Tried to account for with modeling
6:23 Antibiotics, AI and common infections
7:23 Fifty different variables
8:23 Patient specific factors
9:10 Antipsychotics and dementia
10:10 New antipsychotic use increased risk of pneumonia
11:10 Care providers
12:42 End
0:45 Breast cancer and lymph node removal
1:47 Usual care survival 90%
2:45 One percent over five years
3:00 Rate of hospitalization in chronic kidney disease
4:00 Outcomes the same
5:01 Usual care pretty good
6:01 Engage physicians and patients early
6:20 Paxolvid indications
7:20 Twelve or thirteen days to resolution
8:23 Early Parkinson's medicine
9:23 12 months of treatment
10:23 Should enroll more?
11:57 End
0:35 Brain size over the last few decades
1:35 About a 7% greater volume
2:35 Bigger brains start in early childhood
3:55 Biosimilar costs
4:53 Cost about 10% higher
5:45 Does delirium predict dementia?
6:46 Recurrent delirium with dose response
7:47 Programs to reduce delirium in older patients
8:51 Multidrug resistant organisms, iodine and chlorhexidine
9:52 Decolonize every five days
11:04 Don't need surveillance
12:27 End
0:42 Molnupiravir, COVID-19 and immunocompromised people
1:42 Samples up to 44 days post-treatment
2:42 Causes mutagenesis
3:44 Ongoing surveillance?
4:14 Oral steroids in preschool wheeze
5:21 Greater reduction in wheezing severity score
6:21 How often it recurs?
6:33 Use of machine learning to estimate CVD risk with radiographs
7:35 Compared with 2000+ with known risk
8:35 Routine chest X-ray informs risk
9:35 Exercise and sleep quality
10:35 Physically active at beginning and 10 years later
12:12 End
0:40 Aspirin for fatty liver disease
1:40 Low dose aspirin for six months
2:40 Primary prevention?
3:03 Donor heart acceptance
4:03 Just shy of 14,000 donors
5:03 More likely to have antibodies
5:45 Diagnosing Parkinson's with skin biopsy
6:45 Could detect in between 92-100%
7:45 Diagnosis of Lewey body dementia
8:45 Medication abortion before and after Dobbs
9:46 Provisions increased
10:46 Sued the FDA
12:12 End
0:38 Stroke after bivalent COVID-19 vaccine
1:35 No increased risk with this vaccine alone
2:32 Public messaging
2:41 Personalized oxygen settings for patients in the ICU
3:41 Lower level resulted in more days alive without life support
4:41 Lowering blood glucose?
5:42 Verify in randomized trials
6:43 Risk of autism in kids in moms on anti-seizure meds during pregnancy
7:43 Increased risk whether on medicine or not
8:46 Treatment of early breast cancer
9:46 CDK4/6 inhibitor
10:46 No significant side effects
11:37 Younger than median age at diagnosis
12:16 End
0:39 How to treat blocked stents
1:40 Over a year does reblockage occur?
2:40 Bypass may be more durable in some
3:00 Treating ADHD with medicines and mortality
4:00 Mean age at diagnosis 17.4 years
5:00 Still questions remain
6:00 6% of youths worldwide
6:25 THC and marijuana use in youths in the US
7:25 About 11% use over preceding year
8:25 Similar to tianeptine and kratom?
9:10 Screening for colorectal cancer
10:10 Genomic alterations detection
11:10 Stool sample collected
12:06 End
0:31 Microplastics and arteries
1:31 Looked at plaque in 304 patients
2:31 May have to do with baseline risk factors
3:31 More questions than answers
3:42 Worldwide obesity and risk of developing Type 2 diabetes
4:42 Obesity accelerating worldwide
5:42 Identify and stop the process
6:42 Underweight birthweight and overweight at 20
7:44 Steps in the sedentary
8:44 Total daily steps and sedentary lifestyle
9:45 About three miles
10:07 Deaths due to alcohol use
11:08 58 alcohol-related conditions
12:08 Dramatic increase over a short period of time
13:18 End
0:41 Cognition and memory after Covid
1:41 More severe disease leads to greater deficits
2:41 Severity related to strain of virus
3:26 Cardiac rehabilitation
4:26 The earlier the better
5:26 Automatic referral and navigator
6:30 Medicaid expansion and healthcare workers
7:30 Lower income workers on Medicaid
8:31 Bigger safety net
9:31 Trickle down is not a good strategy
10:00 Antibody to IgE
11:00 Children and adolescents with food allergy
12:00 Study participants admired
12:41 End
0:35 Method of use in drug overdose deaths in 2022
1:35 Smoking most common
2:30 Smoking, snorting, injection and ingestion
3:20 Effectiveness and safety of telemedicine abortion
4:20 99.8% NOT followed by an adverse event
5:20 Multiple groups benefit
6:20 Women who experience unintended pregnancy
7:00 New therapy for autoimmune diseases
8:00 How expensive are they?
8:36 Biomarkers previous to Alzheimer's
9:36 Tau and total tau
10:36 Very long follow-up
11:36 Back up treatment very early on
12:41 End
0:40 Who gets a donor heart?
1:41 Mechanical support system
2:42 Assess new guidelines
3:32 E-cigarettes in helping people stop smoking
4:32 Validated abstinence at 6 months
5:32 Doesn't stop nicotine use
6:32 Are deleterious effects
7:01 Reversing anticoagulation in hemorrhagic stroke
8:01 Almost 10,000 such strokes
9:01 Not as much of a barrier to reverse
9:20 Online program for long Covid
10:20 Health related quality of life outcome
11:20 Applied generally?
12:20 Related to deconditioning
13:06 End
0:34 NASH treatment
1:34 Two dosages and placebo
2:32 Similar incidence of adverse events
3:32 Minor effects on heart or bone?
4:15 Psoriasis treatment
5:15 Decreased plaques by 75%
6:05 Human milk, preterm infants, neurodevelopment
7:05 Black infants 52%
8:07 Decreased necrotizing enterocolitis
9:14 Uric acid levels and gout flares
10:15 3600 patients with gout
11:15 Keep levels at five or below
12:15 End
0:33 Long Covid and the complement system
1:33 Top biomarkers identified
2:32 Which complement pathway involved?
3:35 Identify those at risk
3:50 Remission of type 2 diabetes and health outcomes
4:50 Reduced rate of CKD and CVD
5:50 1200 to 1800 kCal per day
6:50 Direct trial in UK
7:03 USPSTF screening for speech and language disorders
8:03 No studies evaluate screening
9:03 Different in different cultures
9:16 Out of pocket costs for patients with cancer and high deductible plans
10:17 Over 2700 in high deductible group
11:15 Sacrificed non-cancer and primary care
12:25 End
0:30 Cancer diagnosis after weight loss
1:30 Two times the frequency
2:33 PFAS guidance for clinicians
3:30 Half-life of eight or more years
4:31 Increased preeclampsia
5:31 Screen water supply
6:23 Understanding how older adults use health care system
7:23 Overdiagnosis, hypervigilance, indicated?
8:23 World Economic Forum on women's health gap
9:23 Avoid 24 million life-years lost
10:23 Ischemic heart disease, tuberculosis
11:21 Women pay more for health insurance
12:34 End
0:32 Long term outcomes in heart failure
1:32 Defibrillator with pacing
2:30 Like putting in a pacemaker
2:50 Congenital syphilis
3:50 Consequences for neonate dire
4:50 Time sensitive treatment
5:50 Almost 4000 cases in 2022
6:30 Breast cancer mortality in last fifty years
7:30 Hormone negative screening very important
8:15 Palliative care in two populations
9:15 Nurse intervention with social worker effective
10:15 Needs to be resourced
11:15 Resistance by some clinicians
12:30 End
0:40 Incentivizing dialysis centers
1:40 Over 1000 dialysis centers
2:40 How to adjust for neighborhood?
3:41 Comprehensive approach needed
4:00 Vegetarian diet and COVID-19 risk
5:03 Importance of diet and disease
6:00 Immunity and foods
6:12 Diagnostic errors in hospitalized patients
7:12 Problems assessing the patient
8:18 Novel proteomics-based cancer screening
9:18 10 proteins with high accuracy
10:18 Different in men and women
11:18 Most useful biomarkers the low concentration ones
12:05 End
0:47 Temporomandibular disorders and management
1:47 10cm visual analog scale
2:47 In subtypes expect some variation
3:36 Which relieves pain and which improves function
4:27 Opening the blood brain barrier and using an antibody for Alzheimer's
5:27 Applied on one side of brain
6:27 Does it reverse or halt dementia?
7:00 A multidomain intervention in preconception through early childhood
8:00 Was helpful in childhood outcomes
9:00 Don't know which factor was most effective
10:00 How to assess factors separately
10:15 IV drug for early atrial fibrillation
11:15 Phase two study
12:43 End
If you are a faculty or staff member or student of TTU, TTUHSC, TTUHSC El Paso or
ASU and think you may have COVID-19 (coronavirus), Email us ElpCovidResponse@ttuhsc.edu
or call 915-215-SICK(7425) to speak with a nurse.