0:45 Steps and CVD
1:42 40-50% lowered risk
2:45 Consider an electronic device to help
3:20 Family income and morbidity and mortality in children
4:20 Association with lower income and health outcomes
5:20 Wasn't due to differential access to medical care
6:20 Cessation of expanded credit
6:40 Association of serotonin receptor with obesity and behavior
7:40 Receptor in the hypothalamus
8:45 Can increase suppressant molecule
9:00 Unionization among health care workers
10:08 More likely to have employer-paid health insurance
11:01 Only 8% of physicians unionized
12:05 May offer leverage if they are corporate employees
12:58 End
0:36 Diagnostic errors in the ED
1:35 About 370,000 per year
2:35 Female and non-White experienced more
3:35 Spine care randomized trial
4:35 How much did it cost the healthcare system?
5:35 Usual care comparison
6:25 Alcohol and drug prevalence in road user accidents
7:25 Active THC at 25%
8:28 National epidemic
8:44 Advent themed exercise
9:44 Easy elf
10:45 Calendar with dates
12:23 End
0:43 New bispecific antibodies
1:44 Two arms that can be manipulated separately
2:44 Will antibodies be patient specific?
3:00 Vigorous intermittent lifestyle physical activity
4:00 The more VILPA the lower your risk
5:01 Also in exercisers
6:00 Osteoarthritis pain, exercise and weight loss
7:00 Both groups experienced pain reduction
8:00 If it showed a benefit
8:18 Mindfulness training, exercise and cognitive function
9:18 Hippocampal volume examined
10:20 Delay cognitive impairment?
11:28 End
0:38 Medicare Advantage and outcomes from heart attacks
1:35 No difference in mortality
2:35 If you want to pick your own physician
2:40 Alcohol and drug overdose deaths in those 65 and older
3:40 Higher for non-Hispanic black men
4:40 Dramatic increase in things like fentanyl
5:30 Tumor infiltrating lymphocytes and melanoma
6:30 Progression free survival doubled
7:30 Use earlier in disease course
7:40 13 valent pneumococcal vaccine and pneumonia hospitalizations
8:40 Varying types of pneumonia
9:40 Don't get vaccine very often
10:35 Vaccine helps in high risk individuals
11:40 End
0:40 Community-based COVID-19 testing and hospitalizations
1:40 In those without symptoms
2:42 Conducted in a community with higher deprivation
3:46 Inhaled particulate accumulation with age
4:48 Lymph nodes have accumulated particles
5:45 Any way to get rid of it?
6:10 Motorcycle accidents and organ transplants
7:13 More when motorcycle rallies taking place
8:14 Need to educate about organ donation
9:15 Much more likely on a motorcycle
9:33 Training teen drivers with ADHD
10:35 Tried to distract the kids
11:35 Switch to skill training
12:54 End
0:40 The global burden of bacterial infections and death
1:40 Four times as many deaths in low income countries
2:40 Treating the right bacteria
3:10 Can we associate hearing loss with dementia?
4:12 1200 participants
5:12 Three previous studies
6:12 Social withdrawal and depression
6:45 Breathlessness in COPD
7:45 Treated over three weeks with low dose opioids
8:30 Skipping cervical cancer screening
9:30 How many women still being screened?
10:30 Two normal HPV tests
11:30 If you've had negative screening before
12:33 End
0:31 Second COVID-19 infection consequences
1:35 Risk elevated regardless of vaccination status
2:35 Is it the same variant?
3:35 Older and sicker individuals?
3:55 New blood pressure medicine (NEJM)
4:55 In addition to their existing medicines
6:00 Tobacco use among U.S. youth
7:00 Almost 14% of Alaskan or Native American
8:05 State and federal interventions underway
9:00 Screening for OSA in nonsymptomatic individuals (JAMA)
10:01 Does it affect outcomes?
11:00 As many as a third of men
12:10 End
0:51 Heart attack treatment times
1:51 Only 17% of the time by guidelines
2:51 Each hospital must evaluate
3:50 Thrombolytic therapy
4:01 Pemafibrate and cardiovascular outcomes
5:01 67% with previous CVD
6:04 Higher incidence of adverse renal events
6:23 Refractory defibrillation
7:23 Double defibrillation had higher survival
8:23 Just experience
8:30 Early treatment of atrial fibrillation
9:30 Much less recurrent fibrillation
10:30 Remodels atrial tissue
11:30 Both done safely in experienced centers
12:49 End
0:40 Hormone therapy for chronic disease prevention
1:40 Lower risk of colorectal cancer, diabetes and fractures
2:40 Is there a rationale to take this?
3:40 Timing hypothesis
4:40 Careful not to exclude vasomotor symptom relief
5:10 Unintended pregnancy and outcomes for mother and child
6:10 Higher risk of low birth weight
7:12 Depression and psilocybin
8:12 Development of a relationship with a therapist prior
9:12 Casts doubt on utility in long haul
10:25 Direct oral anticoagulants for atrial fibrillation
11:41 Apixaban seems best
12:49 End
0:37 Physical activity and Covid vaccination
1:37 High activity 86% effective
2:37 Quarantine and isolation?
3:00 Detection of poliovirus in sewage
4:01 118 genetically linked isolates found
5:01 Surveillance tool powerful
6:01 Identify specific genotypes
6:30 Changes in diet and mortality
7:30 Thirteen to thirty percent improvement
8:32 Two groups included
9:30 Maternal hypertension and offspring mortality
10:31 Eclampsia associated with highest mortality
11:31 Doesn't show that treatment prevents death
13:00 End
0:38 Medicare recipients and prescription drug costs
1:39 Rose to 27% over 10 years
2:40 No limits on prices of new drugs
3:14 Burden of Proof Studies
4:14 Smoking and lung cancer
5:15 Assess conflicting studies
6:15 You replace foods with something else
6:34 Antimicrobial resistance in European region
7:36 Bloodstream infections, respiratory infections
8:35 Global travels spreads these bugs
8:48 Vaping prevention with ads
9:48 Any impact on susceptibility?
10:52 How to get them to watch
12:00 End
0:44 Oral glucose tolerance tests versus HbA1c
1:44 How many had elevated HbA1c?
2:45 Much easier test than oral glucose tolerance
3:10 Diagnosing idiopathic pulmonary fibrosis
4:10 Nonspecific symptoms
5:10 Using data already in the electronic health record
6:11 Using information on hand
7:00 Neurodegenerative disease risk in rugby players
8:00 Not higher death rate, twice as likely for neurodegeneration
9:00 The tackler being injured
9:30 Maternal consumption of ultraprocessed foods
10:30 Three thousand mother child pairs
11:30 Ultraprocessing and inflammation
12:31 End
0:40 Devices to prevent strokes during TAVR
1:40 Approved on basis of debris presence
2:40 Overall risk of stroke is low
3:20 ICU care in the ED
4:20 Economic drivers?
5:20 ICU doc floors away
6:20 Also board certified in critical care medicine
6:40 First-line therapy for Type 2 diabetes
7:40 Benefits in mortality and other outcomes
8:40 In people without existing heart disease
9:12 AI look at the retina and prediction of mortality
10:12 Vascular photographs and AI interpretation
11:14 Offers no additional value
12:55 End
0:41 Neurologic long COVID-19
1:38 42% increased risk
2:38 Across all ages increased risk
3:00 USPSTF syphilis screening update
4:00 Women's rate has nearly tripled
5:00 Make individuals aware
5:55 Bionic pancreas
6:55 Type 1 diabetes
7:55 Didn't quantitate carbohydrate
8:35 Weights in addition to aerobic exercise
9:35 Additional mortality benefit in addition to aerobic
10:35 Doesn't look at duration of activity
11:35 Usually less than 10% meet activity guidelines
13:00 End
0:38 Alzheimer's and multivitamins
1:36 Multivitamins slowed rate of progression
2:36 Slight benefit
3:36 Uniform benefit
3:40 CAR-T therapy and relapse
4:40 Blood factors to predict
5:26 Genetic risk factors and healthy years
6:26 Maybe see genes and disease in the future
7:26 Is it genes or evironment?
8:03 Active surveillance for prostate cancer and outcomes
9:02 Most with prostate cancer in active surveillance
10:02 The younger you are with cancer
11:01 Does it apply to Black men?
12:00 End
0:44 Screening for Type 2 diabetes in children
1:44 Don't know the benefits
2:44 During the pandemic increasing
3:44 How well does that treat it?
4:30 Categorizing foods and mortality
5:30 Cardiovascular and all-cause mortality
6:30 Higher mortality from both
7:30 Increased inflammation and CVD
8:35 Artificial sweeteners and CVD
9:35 Frequently found in ultraprocessed foods
10:23 Steps, intensity, and mortality
11:23 Cancer and diagnosis
12:54 End
0:43 Preventing acute kidney injury in cardiac catheterization
1:43 Point of care clinical decision support
2:43 Audit and feedback
3:30 Autoimmune and cardiovascular diseases
4:30 23.3 events per 1000 patient years
5:30 Even degenerative heart disorders
6:26 Reducing use of X-rays where they may not be useful
7:30 Looked at 3800 practitioners
8:30 Physicians get upset about being told
9:20 Use of SGLT2 inhibitors and GLP1 agonists in ethnic groups
10:20 Self identified race
11:20 There is some disparity
12:51 End
0:43 Looking at sewage for emerging COVID-19 variants
1:42 Capture all the viruses magnetically
2:42 Capture cryptic transmission
3:42 Detection 14 days earlier
4:30 Increased risk for heart attack, stroke or PE after COVID-19 vaccination
5:31 30% increased risk with adenovirus vaccine
6:01 Plasma antigens and clinical course of hospitalized patients with COVID-19
7:01 Elevated baseline antigen levels and worse outcomes
8:03 Many patients already treated
9:10 Predictors of outcomes related to traumatic brain injury (TBI)
10:15 Measured proteins seen after CNS injury
11:15 If we can predict outcome we can apply therapy
12:03 End
0:37 Physical activity and Covid infection
1:37 Greatest benefit by 500 METS
2:37 Tolerate viral illnesses better
3:39 Statin use update
4:39 Greater than 10% risk
5:39 Guidelines based largely on men
6:36 Not risky
7:02 Getting office workers moving
8:03 Electronic reminders
9:04 Organization theory, teamwork
10:04 How they felt
10:20 Global burden of cancer and modifiable risk factors
11:20 Changed geographically across the globe
12:03 End
0:40 Thromboembolism in people hospitalized with Covid versus flu
1:40 60-100% increased DVT or PE
2:40 Continue after hospitalization?
3:44 Effect of remote ischemic conditioning in stroke
4:45 Outcomes five percent improved
5:45 Have to treat 100 to improve five
6:48 Biologic plausibility?
7:10 Treating monkeypox clinically
8:10 Lack of evidence to guide clinical decision making
8:43 Treating gestational diabetes
9:45 Several hundred in each arm
10:45 Maybe lower glucose level would help?
11:56 End
0:45 Post-COVID-19 syndromes associated with variants
1:45 Systemic inflammatory cluster
2:43 Treatment of asymptomatic kidney stones
3:45 Time to relapse 75% longer with treatment
4:45 New techniques and equipment
5:45 Millions of people with stones
6:05 Two studies in intracranial atherosclerosis
7:05 Also got an additional antiplatelet agent
8:05 Risk of recurrent stroke
9:00 Novel risk marker plasma prostasin
10:01 Significantly associated with both diabetes and cancer
11:30 End
0:40 Fainting or syncope and driving restrictions
1:40 Followed after ED visit for six months
2:40 Not able to assess risk better
2:55 Pharmacologic treatment of insomnia
3:55 Two medications with favorable profile
4:55 Melatonin had no effect
5:20 Worldwide burden of COPD
6:20 More people with it even with declining percentage
7:25 Women disproportionately affected in low income countries
7:50 Labeling of prepared foods in supermarkets
8:50 Bakery and deli items decreased
9:50 Education not sufficient for behavior change
10:50 An app that might help
11:50 Business must be involved in change
12:39 End
0:40 Fourth dose of Covid vaccine
1:42 Antibody titers before and after third and fourth dose
2:42 Nothing about how often vaccines needed
3:40 Cardiometabolic complications of Covid
4:40 Six fold increase in cardiovascular disease
5:40 Atrial arrhythmia in acute phase
5:55 Increases in gestational diabetes
6:55 Prepregnancy BMI
7:56 Need to understand better
8:40 Drug overdose sociodemographics
9:41 Black males over 65
10:53 Intentional and unintentional
11:58 End
0:35 Outrunning a bad diet
1:35 Best outcome with both exercise and good diet
2:35 Need policy-level intervention
3:00 Commonwealth report on health for U.S. men
4:00 Least likely to have a regular doctor
5:01 ED visits instead
5:40 Alcohol consumption and impact
6:41 204 countries and territories
7:42 Change to none if you're younger than 40
8:20 Hangriness
9:20 Accounting for a number of traits
10:20 Changes in insulin or other hormones
11:20 Only 58% had breakfast
12:37 End
0:52 Insight into long COVID-19
1:53 What about the variants?
2:42 Factors related to severe COVID-19 in immunocompromised
3:42 Non-immunocompromised lowest risk
4:42 Vaccination does not decrease death risk if hospitalized
5:15 Oral therapy for COVID-19
6:15 How long in hospital?
7:15 How microtubule disruption works
8:15 Hyaluronic acid injections in knees in BMJ
9:20 560 million worldwide living with knee OA
10:20 Many of the studies haven't been published
11:30 End
0:40 Neurological outcomes for babies whose moms had Covid
1:40 Adjusted for other factors still had twice the risk
2:40 One year of follow up
3:00 Targeting noradrenergic pathways in Alzheimer's
4:00 Large positive effect on apathy
5:00 Have more global effects
5:49 Monkeypox in the UK
6:49 Direct contact spread
7:50 Administration of vaccines?
8:00 Cardiovascular health calculator
9:00 Very rare for people to meet them
10:00 Red, yellow or green and an overall score
11:36 End
0:40 Maternal mortality during COVID-19
1:40 Based on codes related to death
2:40 Immunization helpful
3:25 Computer-based CBT for PTSD
4:25 12 individual sessions or online
5:25 Requires less therapist time
6:30 Smoking cessation for those who've been hospitalized
7:31 Community-based quit line
8:30 Motivated individuals
9:27 Immune aging and life stressors
10:31 Lower naive T-cells
11:32 Other significant associations dropped out
12:43 End
0:47 Omicron and Delta and long Covid,
1:50 Self reported symptom studies
2:50 Lots more since more people are getting infected
3:08 State Medicaid expansion and suicide in adults
4:10 Difference might be linked to increased access to mental healthcare
5:10 Men at higher risk
6:00 USPSTF and supplements and minerals
7:00 May increase risk of cancer
8:00 Only a big longitudinal study will define
9:00 What do you say to a patient?
9:25 Green space and mortality
10:25 All cause mortality in those 65 and older
11:25 For recreational activity?
12:34 End
0:40 Testosterone supplements and cardiovascular outcomes
1:43 Over 20 years of data
2:43 In short term, appears safe
3:00 Tomosynthesis in breast screening
4:03 No difference in interval breast cancers
5:03 Better than either technique
6:02 Surrogate for effectiveness of screening
6:31 Political environment and mortality rates
7:33 Contributions to mortality gap
8:31 Evidence base with regard to policy
9:10 Varenicline and smoking in African Americans
10:10 Varenicline 1mg twice daily
11:10 Less likely to stop smoking
12:10 Multimodality important
13:20 End
