2020 TT HealthWatch Archive

TT HealthWatch – Friday, February 21, 2020

This week's topics include natural killer cells and cancer, CMV vaccine in bone marrow transplant recipients, surprise medical bills, and mutations in bronchial epithelium in smokers and nonsmokers.

0:47 CAR-transduced natural killer cells
1:45 Majority responded without major toxicity
2:46 Manage with a kill switch
3:17 Bone marrow transplant and CMV infection
4:18 Reduced CMV by half
5:06 Mutations in bronchial epithelium in smokers
6:07 Driver mutations increased in smokers
7:07 Telomere length assessed
8:08 Smoking cessation benefits
8:25 Surprise medical bills
9:25 After common elective procedures
10:25 For in-hospital network
12:01 End

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TT HealthWatch – Friday, February 14, 2020

This week's topics include coronavirus update, naloxone laws and dispensing, neurologic disorders and suicide, and medications versus lifestyle changes for diabetes and high cholesterol.

0:41 Coronavirus update
1:41 Slightly elevated prothrombin time
2:41 Death of whistleblower
3:20 Rise in suicide
4:22 Central nervous system infections, others
5:20 Parkinson's about twice as likely
6:23 Can't impose constraints in US
6:49 Medications and lifestyle changes
7:50 Placed on meds and were they associated with lifestyle changes?
8:50 Hard to say medications were to blame
9:48 How does access to naloxone change when scripts aren't needed
10:50 Increased by over 2000%
11:40 May make naloxone over the counter
12:50 End

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TT HealthWatch – Friday, February 7, 2020

This week's topics include coronavirus update, treating burns in kids, CT for lung cancer screening, and primary care physician visits.

0:54 Coronavirus update
1:52 Quarantine for 14 days
2:52 Asymptomatic transmission
3:40 Immediate management of burns in kids
4:40 Almost 10% need skin graft
5:42 People put on salves, aloe vera
6:16 Volume-based CT and lung cancer
7:17 In smaller number of women
8:16 Certain size determines follow up
9:15 Spontaneous resolution of small nodules
9:34 Dropping use of primary care visits
10:35 Routine scheduled visits went down
11:35 More efficient health care?
12:10 End

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TT HealthWatch – Friday, January 31, 2020

This week’s topics include the Wuhan coronavirus, treating H.pylori and gastric cancer, human versus analogue insulin, and one marker of acute kidney injury.

0:54 The new coronavirus
1:52 Fluid from lung samples
2:50 15% died in first analysis
3:50 China making great attempts
4:04 Differences in cardiovascular outcomes in insulins
5:04 Four healthcare delivery systems
6:04 Do not change hard endpoints
7:04 The price gouging is dramatic
7:18 Treating helicobacter pylori infection and gastric cancer
8:18 Treatment with proton pump inhibitors and antibiotics
9:20 Acute kidney injury factor
10:20 Assessed risk at 7 days
11:22 Prove that in a mouse model
13:22 End

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TT HealthWatch – Friday, January 24, 2020

This week’s topics include blood levels of sunscreen ingredients, a new drug for heavy menstrual bleeding in women with fibroids, trying to stave off sepsis, and fish oil and sperm quality.

1:17 Vitamin C, thiamine, and hydrocortisone in sepsis
2:17 Mortality and other endpoints
3:16 Prompt use of antibiotics does help
3:36 Fish oil and sperm quality
4:36 In otherwise healthy men
5:38 Might improve sperm quality decline
6:00 Sunscreen ingredients in plasma and skin
7:00 All six of tested ingredients were in plasma surpassing FDA threshold
8:00 Doesn't indicate harm yet
8:40 Heavy menstrual bleeding and uterine fibroid treatment
9:40 Been used in endometriosis
10:40 Hot flashes associated
11:24 End

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TT HealthWatch – Friday, January 17, 2020

This week’s topics include preventing gout with a diabetes medication, physician time on EHR in outpatient visits, ageotypes, and FDA changes to the approval process and outcomes.

0:48 Personal aging markers and ageotypes
1:48 184 molecules associated with age
2:48 Clinical implications unclear
3:49 Individuals vary a lot
4:17 Physician time on the EHR
5:15 17% of time ordering
6:15 Falls on physician to enter
6:42 Two types of diabetes meds and gout risk
7:43 40% reduction with SGLT2 inhibitors
8:43 Gout affects almost 10 million people
9:06 Looked at 25 years of FDA approval process
10:06 All attempts haven’t improved overall process
11:06 Fewer studies and fewer patients
12:07 End

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TT HealthWatch – Friday, January 10, 2020

This week’s topics include arthritis and depression, AI and physician decisions in hospitalized patients, five ways for doctors to practice presence with patients, and health care hotspotting.

0:48 Healthcare hotspotting
1:45 95% of individuals did receive prescribed care
2:56 Five strategies to foster physician presence
3:58 Prepare with intention
4:56 Physicians would concur
5:58 Many barriers
6:19 Hospital based AI system
7:15 6500 patients
8:13 Guarded about such systems
9:10 Arthritis and depression
10:20 Lots in the southern states in U.S.
11:22 Results in poor compliance
12:22 End

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TT HealthWatch – Friday, January 3, 2020

This week’s topics include the impact of hospital mergers, gene therapy for hemophilia, infections and diabetes control, and alcohol consumption and atrial fibrillation.

0:44 Alcohol consumption and atrial fibrillation
1:44 70 patients in each of two arms
2:44 Almost 60% of Americans drink regularly
3:44 Lost nine or ten pounds
4:24 Gene therapy for hemophilia
5:24 Large gene that needed two procedures
6:26 Not only cost of therapy
6:44 Infections and diabetes control
7:44 Diabetes and poor control had 4X risk
8:45 Mortality as high as 20-25%
9:10 Hospital mergers and quality of care
10:09 Modest decline in patient experience
11:10 So many health systems using to remain profitable
12:13 End

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